产品货号：
Z10921
中文名称：
ALPL抗体
英文名称：
Anti-ALPL Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ALPL Antibody |
| 指标别名 | Alkaline phosphatase;Alkaline phosphatase liver/bone/kidney isozyme;Alkaline phosphatase tissue nonspecific isozyme;ALPL;BLAP;Bone Alkaline Phosphatase;NBAP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | ALPL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Alkaline Phosphatase(21-35aa,EKEKDPKYWRDQAQE),different from the related rat and mouse sequences by two amino acids. |
| 实际分子量 | 57KD/80KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Alkaline phosphatase(ALPL) removes phosphate groups from the 5' end of DNA and RNA,and from proteins,at high pH.Most mammals have 4 different isozymes:placental,placental like,intestinal and non tissue specific(found in liver,kidney and bone).Tissues with particularly high concentrations of ALP include the liver,bile ducts,placenta,and bone.ALPL is the alkaline phosphatase of skin fibroblasts,the tissue-nonspecific type,and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP).ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50kb.Damaged or diseased tissue releases enzymes into the blood,so serum ALP measurements can be abnormal in many conditions,including bone disease and liver disease. |
| Uniprot ID | P05186 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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